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Masanobu Kano Selected Research

Cerebellar Diseases (Cerebellar Syndrome)

1/2021mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease.
1/2018Type 1 metabotropic glutamate receptor and its signaling molecules as therapeutic targets for the treatment of cerebellar disorders.
1/2017Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease.
12/2002mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning.

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Masanobu Kano Research Topics

Disease

4Seizures (Absence Seizure)
01/2021 - 06/2014
4Cerebellar Diseases (Cerebellar Syndrome)
01/2021 - 12/2002
3Schizophrenia (Dementia Praecox)
01/2021 - 01/2012
3Autistic Disorder (Autism)
01/2021 - 06/2014
3Tuberous Sclerosis (Bourneville's Disease)
01/2021 - 06/2014
3Epilepsy (Aura)
01/2021 - 05/2015
3Ataxia (Dyssynergia)
01/2021 - 12/2002
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 06/2014
3Spinocerebellar Ataxias (Spinocerebellar Ataxia)
01/2018 - 06/2002
3Neoplasms (Cancer)
01/2013 - 06/2009
2Autism Spectrum Disorder
01/2021 - 01/2017
2Pain (Aches)
09/2014 - 02/2014
2Atrophy
06/2014 - 02/2009
2Sarcoma (Soft Tissue Sarcoma)
01/2013 - 08/2011
2Cognitive Dysfunction
12/2009 - 07/2009
1Lennox Gastaut Syndrome
01/2021
1Myoclonic Epilepsies (Myoclonic Encephalopathy)
01/2021
1Drug Resistant Epilepsy
01/2021
1Craniosynostoses (Craniosynostosis)
01/2020
1Partial Epilepsies (Epilepsy, Partial)
01/2020
1Neuroinflammatory Diseases
10/2019
1Obesity
01/2019
1Bradycardia
07/2018
1Bundle-Branch Block (Fascicular Block)
07/2018
1Frontotemporal Dementia (Semantic Dementia)
01/2018
1Temporal Lobe Epilepsy
01/2018
1Autoimmune Diseases (Autoimmune Disease)
01/2018
1Status Epilepticus (Complex Partial Status Epilepticus)
01/2016
1Fever (Fevers)
01/2015
1Hypokalemia
01/2015
1Hypertrophy
06/2014
1Sclerosis
06/2014
1Microcephaly
06/2014
1Synovial Sarcoma (Synovioma)
09/2012
1Acrocephalopolydactylous Dysplasia
04/2011
1Griscelli syndrome type 1
04/2011
1Nervous System Diseases (Neurological Disorders)
04/2011
1Dementia (Dementias)
12/2009

Drug/Important Bio-Agent (IBA)

7EndocannabinoidsIBA
01/2021 - 02/2014
4metabotropic glutamate receptor type 1IBA
01/2021 - 12/2002
4Monoacylglycerol LipasesIBA
10/2019 - 09/2014
4CB1 Cannabinoid Receptor (CB1 Receptor)IBA
01/2019 - 09/2014
4EnzymesIBA
01/2019 - 09/2014
4glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA
01/2019 - 09/2014
3CannabinoidsIBA
01/2021 - 05/2015
2Mechanistic Target of Rapamycin Complex 1IBA
01/2019 - 06/2014
2Glutamic Acid (Glutamate)FDA Link
01/2018 - 01/2012
2polyglutamineIBA
01/2017 - 02/2009
2Lipoprotein Lipase (Diacylglycerol Lipase)IBA
01/2016 - 01/2015
2AntigensIBA
01/2013 - 06/2009
2Proteins (Proteins, Gene)FDA Link
01/2013 - 06/2002
2Protein Subunit VaccinesIBA
09/2012 - 06/2009
2Mutant Proteins (Protein, Mutant)IBA
02/2009 - 06/2002
1Arginine (L-Arginine)FDA Link
01/2021
1neuroligin 3IBA
01/2021
1Vitamin B 6IBA
01/2021
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2021
1Amino AcidsFDA Link
01/2021
1CannabidiolIBA
01/2021
1NeuroliginsIBA
01/2021
1Histone MethyltransferasesIBA
01/2020
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2020
1MSX2 proteinIBA
01/2020
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2019
1LipidsIBA
01/2019
1Hyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIBA
07/2018
1ProgranulinsIBA
01/2018
1AutoantibodiesIBA
01/2018
1gamma-Aminobutyric Acid (GABA)IBA
01/2018
1Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
01/2018
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018
1Protein Isoforms (Isoforms)IBA
01/2017
1RNA Splice SitesIBA
01/2017
1Serotonin (5 Hydroxytryptamine)IBA
01/2017
1Codon (Codons)IBA
01/2017
1Kainic Acid (Kainate)IBA
01/2016
1Phospholipases (Phospholipase)IBA
01/2015
1Anti-Arrhythmia AgentsIBA
01/2015
1LipopolysaccharidesIBA
01/2015
1Dinoprostone (PGE2)FDA Link
01/2015
1AM 251 (AM251)IBA
09/2014
1JZL 184IBA
09/2014
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
09/2014
1Analgesics (Analgesic Drugs)IBA
09/2014
1Acetic Acid (Vinegar)FDA LinkGeneric
09/2014
1Formaldehyde (Formol)FDA Link
09/2014
1trans-sodium crocetinate (crocetin)IBA
06/2014
1TOR Serine-Threonine KinasesIBA
06/2014
1ProstaglandinsIBA
02/2014
1Messenger RNA (mRNA)IBA
01/2013
1Biomarkers (Surrogate Marker)IBA
01/2013
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2012
1N-Methylaspartate (NMDA)IBA
01/2012
1Myosins (Myosin)IBA
04/2011
1Amyloid beta-PeptidesIBA
12/2009
1Antihypertensive Agents (Antihypertensives)IBA
12/2009
1Angiotensin Receptor AntagonistsIBA
12/2009
1olmesartanIBA
12/2009

Therapy/Procedure

2Immunotherapy
08/2011 - 06/2009
1Therapeutics
01/2013